Samantha Gooneratne and Vincent Ho were recently awarded a bursary each from bioProcess UK to attend the Annual bioProcess UK Conference 2008 at Brighton from 26-27 November. They will also be presenting their research work in the form of posters at the conference.
The title of Vincent's poster will be Magnetic Cell Patterning using Streptavidin Paramagnetic Particles. His work entails labelling mammalian cells magnetically, by binding magnetic particles onto cell surfaces and using magnetic fields to target these magnetically labelled cells and precisely position them. The advantage of his methodology is that it does not require cell uptake of magnetic materials, which is a variable process and his method can be adapted for various cell types.
The title of Sam's poster is Continuous-Mode Solid-Phase Organic Chemistry Reactor for Manufacture of Radiopharmaceuticals. The work entails incorporating the use of Solid-Phase Organic Synthesis in a Packed-Bed Reactor, in order to manufacture a 'cold' (i.e. non-radioactive) model of a radiolabelled metabolite used in Positron Emission Tomography. These radiotracers are currently manufactured using conventional solution-phase chemistry, with subsequent purification by High Performance Liquid Chromatography. It is believed that the proposed method would enable simultaneous continuous processing and purification, thereby improving upon processing time and cost with no compromise of product purity.
Vincent and Sam are members of the BioScience Engineering Group, supervised by Prof Nigel Slater.