Five members of the Department, Jacob Brubert, Romilde Kotze, Ingrid Wong, Tian Tian and David Fairen-Jimenez, are amongst the winners of the Cambridge University Entrepreneurs (CUE) £1K competition 2014-2015. All competed in the Technology & Life Sciences category.
For the £1k competition, each team had to write a 1500 word executive summary to show that their idea has wings.
Jacob Brubert, Romilde Kotze and Ingrid Wong's idea (with Paul De Sciscio from the Department of Engineering) was Cambridge Cardiology.
Aortic Stenosis is a heart condition affecting 6 million people across Europe. The only definitive therapy is valve replacement traditionally performed via open heart surgery. Catheter based intervention has significant advantages over open heart surgery in terms of reduced mortality, hospital stay and recovery time. Unfortunately the design of catheter based valves make them a once off procedure limiting their use to high risk patients aged >75 years. At Cambridge Cardiology we believe that catheter based valve replacement should be the standard of care for all patients with Aortic Stenosis. To achieve this we have developed a first of its kind removable transcatheter valve.
Jacob Brubert and Romilde Kotze are PhD students. Ingrid Wong is on the MBE course.
Dr David Fairen Jimenez and Tian Tian, with Andrew Marsden, Thomas Fry and Dr Claudia Percivalle proposed MOFs i-Teams.
Metal-organic frameworks (MOFs) are porous materials which can store and release gases. At the same pressure, a tank filled with MOFs can store 4x as much gas as an empty tank. Historically, MOFs have been synthesised as powders, using binder or pressure to shape them into pellets. Our patented technology enables the manufacture of MOFs as large pellets without the need for binder or pressure. Our monolithic MOF brings advantages of mechanical robustness, hydrophobicity, and 3x the volumetric capacity of traditional powdered MOFs. In collaboration with Cambridge Enterprise, this award will allow us to start defining the business plan for a spin-out company. We aim to use this new technique to manufacture a range of MOFs to meet the needs of different markets.
David Fairen Jimenez is a Royal Society University Research Fellow and Tian Tian is a PhD student.
The teams will now go on to enter the £5k competition where they must convince judges and investors that the idea can fly by producing a 3500 word business plan.