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Naked Scientists

last modified Jun 19, 2014 11:10 AM
BBC Radio Cambridgeshire broadcast featuring Krishnāa Mahbubani, Graham Christie and Alex Routh
Naked Scientists

Krishnāa Mahbubani (left) and Graham Christie (right) with Naked Scientists Chris Smith and Kat Arney. Click on the image to view it full screen.

Three of our lecturers were on BBC Radio Cambridgeshire on Sunday 8th June 2014, talking about different ways to protect biological things through harsh environments.

Krishnāa Mahbubani, Graham Christie and Alex Routh were interviewed by Naked Scientists, Chris Smith and Kat Arney.

Graham discussed how his group are engineering bacterial spores - nature’s most resilient cells - to produce biopharmaceutical proteins that are stored inside the protective capsule of the spore.  If realised, this could deliver therapeutic products with essentially indefinite ambient-stable shelf-lives.

Krish has been looking at ways of getting bacterial vaccines to developing countries without having to keep them refridgerated. Unless kept cool, there is a danger that the bacteria will multiply and so the patient could be given the disease rather than a vaccination against the disease. Removing water by vacuum drying puts bacterial vaccines into suspended animation so that they are stable at higher temperatures.

Alex discussed his group's work on encapsulation of biological matter in colloidosomes. They have shown the protection of bacteria through stomach conditions and enzymes in washing liquids. The technique is easily adaptable to any biological material and will hopefully be extended to look at oral vaccines.

Naked Scientist page, including links to all the chapters and transcripts

Listen to the podcast

The programme was also broadcast nationally on BBC 5 Live, issued as a podcast under the banner "5 Live Science" and it went out across Australia on ABC Radio National.

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