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Department of Chemical Engineering and Biotechnology

 

UFOs by  Tom Turmezei

This is a colourised confocal microscopy image of neuroblastoma cell labelled with a fluorescent dye called DiD. The dye molecules are taken up  directly and activated by the cell membrane. Balls of fluorescence  beneath the membrane surface may be new endocytic vesicles formed by  live cells within the dye incubation period (20 min). These types of  dye are useful because they avoid the need for bulky fluorescent  antibody labelling and hold promise for imaging the co-localisation of  molecules and membrane structures with super-resolution imaging. This  is particularly relevant to my work on the aggregation and propagation  of tau protein in the brains of dementia sufferers, with passage of  tau into cells via endosomes suspected to be essential to the disease  process. By Dr Tom Turmezei, Wellcome Trust PhD Clinical Fellow, Laser  Analytics Group

Latest news

Nanoparticles used to transport anti-cancer agent to cells

16 September 2019

Researchers from our Adsorption and Advanced Materials group have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.

August paper of the month: Ultralow-field nuclear magnetic resonance of liquids confined in ferromagnetic and paramagnetic materials

16 September 2019

Researchers from our department’s magnetic resonance research centre show new insight provided by ultra-low-field techniques.

Our MPhil in Biotechnology wraps up a successful first year

4 September 2019

Our MPhil in Biotechnology 2018-19 course came to an official close last week with their first student cohort presenting their work at the course symposium.