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Stem cell research

Matthew Lim
A colony of mouse epiblast stem cells. Credit: I. Gabrielle M. Brons Matthew Lim gained his PhD in November 2004, after working with the Magnetic Resonance and Catalysis Group. He currently holds an EPSRC Overseas Fellowship at the Life Science Interface.

Dr Matthew Lim has been awarded £8,000 from the Cambridge MIT Institute (CMI) to support a project entitled Engineering Transplantable Tissue from Stem Cells.

The project will be carried out in collaboration with Professor Roger Pedersen and Dr Gabrielle Brons in the Department of Surgery at Cambridge and Professor Linda Griffith in the Department of Biological Engineering at MIT.

They will be growing tissue from Mouse Epiblast Stem Cells and assessing the transplantation potential of these novel tissues by immunological studies. These novel stem cells were discovered by the Pedersen Lab and their paper in Nature describing the derivation of these cells was made available for online download on the 27th June 2007.

This finding was widely featured in the news as these Stem Cells derived from post-implantation mouse embryos are more like Human Embryonic Stem Cells than existing Mouse Embryonic Stem cells and thus may offer a new model for understanding how human cells grow and differentiate.

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