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Department of Chemical Engineering and Biotechnology




1.         Mohamed MYH, Christie G.2018. A system for the expression and release of heterologous proteins from the core of Bacillus subtilisspores. FEMS Microbiol Lett 365.

2.         Manetsberger J, Ghosh A, Hall EAH, Christie G.2018. Orthologues of Bacillus subtilis spore crust proteins have a structural role in the Bacillus megateriumQM B1551 spore exosporium. Appl Environ Microbiol doi:10.1128/aem.01734-18.

3.         Ghosh A, Manton JD, Mustafa AR, Gupta M, Ayuso-Garcia A, Rees EJ, Christie G.2018.Proteins Encoded by the gerP Operon Are Localized to the Inner Coat in Bacillus cereusSpores and Are Dependent on GerPA and SafA for Assembly. Appl Environ Microbiol 84.

4.         Wang S, Zhou KX, Christie G, Wilson DI.2018. Development of zero discharge net flow fluid dynamic gauging for studying biofilm and spore removal. Food Bioprod Process doi:

5.         Manton JD, Xiao Y, Turner RD, Christie G, Rees EJ.2018. ELM: super-resolution analysis of wide-field images of fluorescent shell structures. Methods Appl Fluoresc 6:037001.

6.         Ke P, Batalha IL, Dobson A, Tejeda-Montes E, Ekizoglou S, Christie G, McCabe J, van der Walle CF.2018. Novel salts of dipicolinic acid as viscosity modifiers for high concentration antibody solutions. International Journal of Pharmaceutics 548:682-688.

7.         Xu Zhou K, Ionescu A, Wan E, Ho YN, Barnes CHW, Christie G, Wilson DI.2018. Paramagnetism in Bacillus spores: Opportunities for novel biotechnological applications. Biotechnol Bioeng 115:955-964.

8.         Zhou KX, Wisnivesky F, Wilson DI, Christie G.2017. Effects of culture conditions on the size, morphology and wet density of spores of Bacillus cereus569 and Bacillus megateriumQM B1551. Lett Appl Microbiol 65:50-56.

9.         Xu Zhou K, Li N, Christie G, Wilson DI.2017. Assessing the Impact of Germination and Sporulation Conditions on the Adhesion of BacillusSpores to Glass and Stainless Steel by Fluid Dynamic Gauging. J Food Sci 82:2614-2625.

10.       Esson D, Gupta S, Bailey D, Wigley P, Wedley A, Mather AE, Meric G, Mastroeni P, Sheppard SK, Thomson NR, Parkhill J, Maskell DJ, Christie G, Grant AJ.2017. Identification and initial characterisation of a protein involved in Campylobacter jejunicell shape. Microb Pathog 104:202-211.

11.       Batalha IL, Ke P, Tejeda-Montes E, Uddin S, van der Walle CF, Christie G.2017. Dipicolinic acid as a novel spore-inspired excipient for antibody formulation. International Journal of Pharmaceutics 526:332-338.

12.       Lanzilli M, Donadio G, Addevico R, Saggese A, Cangiano G, Baccigalupi L, Christie G, Ricca E, Isticato R.2016. The Exosporium of Bacillus megaterium QM B1551 Is Permeable to the Red Fluorescence Protein of the Coral Discosomasp. Frontiers in Microbiology 7:1-8.

13.       Esson D, Mather AE, Scanlan E, Gupta S, de Vries SP, Bailey D, Harris SR, McKinley TJ, Meric G, Berry SK, Mastroeni P, Sheppard SK, Christie G, Thomson NR, Parkhill J, Maskell DJ, Grant AJ.2016. Genomic variations leading to alterations in cell morphology of Campylobacterspp. Scientific Reports 6:1 - 13.

14.       Eijlander RT, Holsappel S, de Jong A, Ghosh A, Christie G, Kuipers OP.2016. SpoVT: From Fine-Tuning Regulator in Bacillus subtilisto Essential Sporulation Protein in Bacillus cereus. Frontiers in Microbiology 7:1-11.

15.       Al-Riyami B, Ustok FI, Stott K, Chirgadze DY, Christie G.2016. The crystal structure of Clostridium perfringens SleM, a muramidase involved in cortical hydrolysis during spore germination. Proteins 84:1681-1689.

16.       Ustok FI, Chirgadze DY, Christie G.2015. Crystal structure of the PepSY-containing domain of the YpeB protein involved in germination of Bacillusspores. Proteins 83:1914-21.

17.       Ustok FI, Chirgadze DY, Christie G.2015. Structural and functional analysis of SleL, a peptidoglycan lysin involved in germination of Bacillusspores. Proteins 83:1787-99.

18.       Manetsberger J, Manton JD, Erdelyi MJ, Lin H, Rees D, Christie G, Rees EJ.2015. Ellipsoid Localization Microscopy Infers the Size and Order of Protein Layers in BacillusSpore Coats. Biophysical Journal 109:2058-66.

19.       Manetsberger J, Hall EA, Christie G.2015. Plasmid-encoded genes influence exosporium assembly and morphology in Bacillus megateriumQM B1551 spores. FEMS Microbiol Lett 362:1 - 7.

20.       Gupta S, Zhou KX, Bailey DM, Christie G.2015. Structure-function analysis of the Bacillus megateriumGerUD spore germinant receptor protein. FEMS Microbiol Lett 362:1 - 6.

21.       Cruz-Mora J, Perez-Valdespino A, Gupta S, Withange N, Kuwana R, Takamatsu H, Christie G, Setlow P.2015. The GerW Protein Is Not Involved in the Germination of Spores of BacillusSpecies. PLoS One 10:1 - 13.

22.       Ustok FI, Packman LC, Lowe CR, Christie G.2014. Spore germination mediated by Bacillus megateriumQM B1551 SleL and YpeB. J Bacteriol 196:1045-54.

23.       Manetsberger J, Hall EA, Christie G.2014. BMQ_0737 encodes a novel protein crucial to the integrity of the outermost layers of Bacillus megateriumQM B1551 spores. FEMS Microbiol Lett 358:162-9.

24.       Ramirez-Peralta A, Gupta S, Butzin XY, Setlow B, Korza G, Leyva-Vazquez MA, Christie G, Setlow P.2013. Identification of new proteins that modulate the germination of spores of Bacillusspecies. J Bacteriol 195:3009-21.

25.       Li Y, Butzin XY, Davis A, Setlow B, Korza G, Ustok FI, Christie G, Setlow P, Hao B.2013. Activity and regulation of various forms of CwlJ, SleB, and YpeB proteins in degrading cortex peptidoglycan of spores of Bacillusspecies in vitro and during spore germination. J Bacteriol 195:2530-40.

26.       Gupta S, Ustok FI, Johnson CL, Bailey DM, Lowe CR, Christie G.2013. Investigating the functional hierarchy of Bacillus megateriumPV361 spore germinant receptors. J Bacteriol 195:3045-53.

27.       Christie G. 2012. Initiation of germination in Bacillusand Clostridiumspores, p 89-106. InAbel-Santos E (ed), Bacterial Spores: Current research and applications. Caister Academic Press, Norfolk, UK.

28.       Christie G, Ustok FI, Lu Q, Packman LC, Lowe CR.2010. Mutational analysis of Bacillus megateriumQM B1551 cortex-lytic enzymes. J Bacteriol 192:5378-89.

29.       Christie G, Gotzke H, Lowe CR.2010. Identification of a receptor subunit and putative ligand-binding residues involved in the Bacillus megateriumQM B1551 spore germination response to glucose. J Bacteriol 192:4317-26.

30.       Setlow B, Peng L, Loshon CA, Li YQ, Christie G, Setlow P.2009. Characterization of the germination of Bacillus megateriumspores lacking enzymes that degrade the spore cortex. J Appl Microbiol 107:318-28.

31.       Christie G, Lowe CR.2008. Amino acid substitutions in transmembrane domains 9 and 10 of GerVB that affect the germination properties of Bacillus megateriumspores. J Bacteriol 190:8009-17.

32.       Christie G, Lazarevska M, Lowe CR.2008. Functional consequences of amino acid substitutions to GerVB, a component of the Bacillus megateriumspore germinant receptor. J Bacteriol 190:2014-22.

33.       Bhatta D, Christie G, Blyth J, Lowe CR.2008. Development of a holographic sensor for the detection of calcium dipicolinate— A sensitive biomarker for bacterial spores. Sensors and Actuators B: Chemical 134:356-359.

34.       Christie G, Lowe CR.2007. Role of chromosomal and plasmid-borne receptor homologues in the response of Bacillus megateriumQM B1551 spores to germinants. J Bacteriol 189:4375-83.

35.       Bhatta D, Christie G, Madrigal-Gonzalez B, Blyth J, Lowe CR.2007. Holographic sensors for the detection of bacterial spores. Biosens Bioelectron 23:520-7.

36.       Leggo PJ, Ledesert B, Christie G.2006. The role of clinoptilolite in organo-zeolitic-soil systems used for phytoremediation. Sci Total Environ 363:1-10.

37.       Madrigal González B, Christie G, Davidson CAB, Blyth J, Lowe CR.2005. Divalent metal ion-sensitive holographic sensors. Analytica Chimica Acta 528:219-228.